A medical supply cart system comprising a cart, a refrigeration device, and a power system. The cart includes an enclosure, a handle, a number of wheels rotatably mounted to the enclosure, and a number of supports each configured to be shifted between an operational position and an access position. The refrigeration device is configured to be positioned in the enclosure and retain perishable medical supplies at a lowered temperature. The power system is configured to power the refrigeration device and includes a number of batteries configured to directly power the refrigeration device, a genset configured to charge the plurality of batteries, and a solar array configured to charge the plurality of batteries.