发明公开
- 专利标题： MUSCLE TARGETING COMPLEXES AND FORMULATIONS FOR TREATING MYOTONIC DYSTROPHY
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申请号： US18303506申请日： 2023-04-19
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公开(公告)号： US20230330247A1公开(公告)日： 2023-10-19
- 发明人: Scott Hilderbrand , Timothy Weeden , John Najim , Stefano Zanotti , Romesh R. Subramanian , Mohammed T. Qatanani , Cody A. Desjardins , Kim Tang , Brendan Quinn
- 申请人： Dyne Therapeutics, Inc.
- 申请人地址： US MA Waltham
- 专利权人： Dyne Therapeutics, Inc.
- 当前专利权人： Dyne Therapeutics, Inc.
- 当前专利权人地址： US MA Waltham
- 主分类号： A61K47/68
- IPC分类号： A61K47/68 ; A61K47/54 ; A61P21/00
摘要：
Aspects of the disclosure relate to complexes and other aspects relate to formulations (e.g., aqueous, lyophilized forms) comprising such complexes comprising an oligonucleotide (e.g., useful for targeting DMPK) covalently linked to an antibody (e.g., anti-TfR1 antibody).
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