A method for calibrating a radio transceiver begins by injecting a low-frequency tone at a transmit power amplifier input of the radio transceiver, where the low frequency tone is at least an order of magnitude lower than the operating frequency of a local oscillator coupled to the transmitter input. The method continues by upconverting the low-frequency tone to produce a plurality of tones at a transmit power amplifier output and then determining which tone of the plurality of tones is a local oscillator feedthrough tone associated with a transmit power amplifier output and which tone of the plurality of tones is representative of an in-phase and quadrature (I/Q) imbalance associated with the transmit power amplifier output. The method continues by determining a DC offset, based on the local oscillator feedthrough tone, where the DC offset is representative of local oscillator feedthrough in the transmit power amplifier output and finally determining, based on the tone representative of an I/Q imbalance, an I/Q offset associated with the transmit power amplifier output.