A computing system is provided, including a processor configured to identify a plurality of measurement sequences that implement a logic gate. Each measurement sequence may include a plurality of measurements of a quantum state of a topological quantum computing device. The processor may be further configured to determine a respective estimated total resource cost of each measurement sequence of the plurality of measurement sequences. The processor may be further configured to determine a first measurement sequence that has a lowest estimated total resource cost of the plurality of measurement sequences. The topological quantum computing device may be configured to implement the logic gate by applying the first measurement sequence to the quantum state.