- 专利标题： USE OF NUCLEOTIDE SYNTHESIS INHIBITORS FOR TARGETED THERAPY IN MLL3/4 COMPASS MUTANT CANCER
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申请号： US18328011申请日： 2023-06-02
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公开(公告)号： US20230390297A1公开(公告)日： 2023-12-07
- 发明人: Ali Shilatifard , Zibo Zhao
- 申请人： Northwestern University
- 申请人地址： US IL Evanston
- 专利权人： Northwestern University
- 当前专利权人： Northwestern University
- 当前专利权人地址： US IL Evanston
- 主分类号： A61K31/519
- IPC分类号： A61K31/519 ; A61K31/4375 ; A61K31/42 ; A61P35/00
摘要：
Disclosed herein are methods and compositions for treating a subject comprising the administration of an effective amount of a nucleotide synthesis inhibitor to a subject in need of treatment for a MLL3/4 COMPASS deficient cancer or a MLL3/4 loss of function mutation.
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