The present disclosure provides a method and a system for area management in a smart city based on an Internet of Things. The method includes obtaining environmental monitoring data in a target area through a sensor network platform, the environmental monitoring data including at least one of air quality data, weather data, and satellite image data, predicting an air pollution situation in the target area through a regional prediction model based on the environmental monitoring data, the regional prediction model being a machine learning model, and sending prompt information, which is determined based on the air pollution situation in the target area, to a user platform through a service platform, wherein the target area is a hexagonal area; and the regional prediction model includes seven regional models and an air quality determination model; wherein a prediction mode of the regional prediction model is an iterative prediction.