- 专利标题： CHIMERIC ANTIGEN RECEPTOR TO CARBOHYDRATE ANTIGENS
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申请号： US17779704申请日： 2020-11-25
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公开(公告)号： US20230058044A1公开(公告)日： 2023-02-23
- 发明人: Vered PADLER-KARAVANI , Yafit ATIYA-NASAGI , Ron AMON , Anat GLOBERSON LEVIN , Tova WAKS , Moran RAWET-SLOBODKIN , Lihi NINIO MANY , Zelig ESHHAR
- 申请人： RAMOT AT TEL-AVIV UNIVERSITY LTD. , ICHILOV TECH LTD. , YEDA RESEARCH AND DEVELOPMENT CO. LTD.
- 申请人地址： IL Tel Aviv; IL Tel Aviv; IL Rehovot
- 专利权人： RAMOT AT TEL-AVIV UNIVERSITY LTD.,ICHILOV TECH LTD.,YEDA RESEARCH AND DEVELOPMENT CO. LTD.
- 当前专利权人： RAMOT AT TEL-AVIV UNIVERSITY LTD.,ICHILOV TECH LTD.,YEDA RESEARCH AND DEVELOPMENT CO. LTD.
- 当前专利权人地址： IL Tel Aviv; IL Tel Aviv; IL Rehovot
- 国际申请： PCT/IL2020/051215 WO 20201125
- 主分类号： A61K35/17
- IPC分类号： A61K35/17 ; C07K14/725 ; C07K14/705 ; C07K14/735 ; C12N5/0783
摘要：
The present invention discloses chimeric antigen receptors that specifically recognize and bind to SLe A carbohydrate antigen with high specificity and selectivity. The invention further provides lymphocytic cells, such as T cells, comprising said CARs, compositions comprising said cells or CARs as well as uses thereof.
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