- 专利标题: New mesothelin specific chimeric antigen receptors (CAR) for solid tumors cancer immunotherapy
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申请号: US17788133申请日: 2020-12-22
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公开(公告)号: US20230068949A1公开(公告)日: 2023-03-02
- 发明人: Cecile SCHIFFER-MANNIOUI , Philippe DUCHATEAU
- 申请人: CELLECTIS
- 申请人地址: FR Paris
- 专利权人: CELLECTIS
- 当前专利权人: CELLECTIS
- 当前专利权人地址: FR Paris
- 优先权: DKPA201970835 20191223
- 国际申请: PCT/EP2020/087673 WO 20201222
- 主分类号: A61K35/17
- IPC分类号: A61K35/17 ; C07K16/30 ; C07K14/725 ; C07K16/28 ; C07K14/705 ; C12N15/90 ; A61P35/00
摘要:
The present invention relates to engineered immune cells expressing new mesothelin (MLSN) specific chimeric antigen receptors (anti-mesothelin CAR) and their use in the treatment of solid tumors, particularly suited for allogeneic cell immunotherapy.
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