- 专利标题： PHOSPHATIDYLCHOLINE LIPID LIPOSOMES AS BOUNDARY LUBRICANTS IN AQUEOUS MEDIA
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申请号： US17984761申请日： 2022-11-10
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公开(公告)号： US20230080018A1公开(公告)日： 2023-03-16
- 发明人: Jacob KLEIN et al. , Ronit Goldberg , Yechezkel Barenholtz , Avi Schroeder
- 申请人： Jacob KLEIN et al. , Ronit Goldberg , Yechezkel Barenholtz , Avi Schroeder
- 申请人地址： IL Rehovot; IL Rehovot; IL Jerusalem; IL Moshav Massuout Yitzhak
- 专利权人： Jacob KLEIN et al.,Ronit Goldberg,Yechezkel Barenholtz,Avi Schroeder
- 当前专利权人： Jacob KLEIN et al.,Ronit Goldberg,Yechezkel Barenholtz,Avi Schroeder
- 当前专利权人地址： IL Rehovot; IL Rehovot; IL Jerusalem; IL Moshav Massuout Yitzhak
- 主分类号： A61K9/127
- IPC分类号： A61K9/127 ; A61L27/50
摘要：
The invention provides a method for lubricating one or more surfaces, comprising applying gel-phase liposomes onto said one or more surfaces, wherein the temperature of said surface(s) at the time of lubrication is below the phase transition temperature Tm of said liposomes. The method can be used for lubricating non-biological surfaces, and also for lubricating the surfaces of a biological tissue in a mammalian subject, e.g., for treating joint dysfunction.