- 专利标题： PIPERIDINE DERIVATIVES AND COMPOSITIONS FOR THE INHIBITION OF NICOTINAMIDE PHOSPHORIBOSYLTRANSFERASE (NAMPT)
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申请号： US17941061申请日： 2022-09-09
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公开(公告)号： US20230110003A1公开(公告)日： 2023-04-13
- 发明人: Kenneth W. Bair , Timm R. Baumeister , Alexandre J. Buckmelter , Karl H. Clodfelter , Bingsong Han , Judith D. Kuntz , Jian Lin , Dominic J. Reynolds , Chase C. Smith , Zhongguo Wang , Xiaozhang Zheng
- 申请人： Valo Health, Inc.
- 申请人地址： US MA Boston
- 专利权人： Valo Health, Inc.
- 当前专利权人： Valo Health, Inc.
- 当前专利权人地址： US MA Boston
- 主分类号： C07D519/00
- IPC分类号： C07D519/00 ; C07D215/48 ; C07D471/04 ; C07D513/04 ; A61K31/4545 ; A61K31/5377 ; A61K45/06 ; A61K31/437 ; A61K31/4709 ; A61K31/497 ; C07D495/04
摘要：
The present invention relates to compounds and compositions for the inhibition of NAMPT, their synthesis, applications and antidotes. An illustrative compound of the invention is shown below:
Formula (I)
Formula (I)
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