Systems and methods for automatic lesion assessment and/or processing imaging data are disclosed. An example intravascular imaging system may include a catheter including an imaging device. A processor may be coupled to the catheter. The processor may be configured to process imaging data received from the imaging device. The processor may be configured to generate a longitudinal section view of a blood vessel from the imaging data received from the imaging device. The processor may be configured to identify a minimum lumen area along the longitudinal section view of the blood vessel, a distal reference point, and a proximal reference. A display unit may be coupled to the processor. The display unit may be configured to show a display including the longitudinal section view of the blood vessel.