- 专利标题： RIP1 INHIBITORY COMPOUNDS AND METHODS FOR MAKING AND USING THE SAME
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申请号： US17843194申请日： 2022-06-17
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公开(公告)号： US20230112865A1公开(公告)日： 2023-04-13
- 发明人: Yan CHEN , Jiaxin YU , Simon SHAW , Ihab DARWISH , Vanessa TAYLOR , Somasekhar BHAMIDIPATI , Zhushou LUO , Rao KOLLURI
- 申请人： Rigel Pharmaceuticals, Inc.
- 申请人地址： US CA South San Francisco
- 专利权人： Rigel Pharmaceuticals, Inc.
- 当前专利权人： Rigel Pharmaceuticals, Inc.
- 当前专利权人地址： US CA South San Francisco
- 主分类号： C07D401/14
- IPC分类号： C07D401/14 ; C07D401/12 ; C07D403/12 ; C07D403/14 ; C07D405/14 ; C07D471/08 ; C07D487/04 ; C07D491/107 ; A61K31/553 ; C07D267/02 ; C07D413/12 ; C07D413/14 ; C07D493/04
摘要：
Disclosed herein are kinase inhibitory compounds, such as a receptor-interacting protein-1 (RIP1) kinase inhibitor compounds, as well as pharmaceutical compositions and combinations comprising such inhibitory compounds. The disclosed compounds, pharmaceutical compositions, and/or combinations may be used to treat or prevent a kinase-associated disease or condition, particularly a RIP1-associated disease or condition.