- 专利标题： DIARYL SUBSTITUTED 6,5-FUSED RING COMPOUNDS AS C5aR INHIBITORS
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申请号： US17931801申请日： 2022-09-13
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公开(公告)号： US20230115912A1公开(公告)日： 2023-04-13
- 发明人: Pingchen FAN , Christopher W. LANGE , Viengkham MALATHONG , Venkat Reddy MALI , Sreenivas PUNNA , Hiroko TANAKA , Yibin ZENG , Penglie ZHANG
- 申请人： CHEMOCENTRYX, INC.
- 申请人地址： US CA San Carlos
- 专利权人： CHEMOCENTRYX, INC.
- 当前专利权人： CHEMOCENTRYX, INC.
- 当前专利权人地址： US CA San Carlos
- 主分类号： A61K31/437
- IPC分类号： A61K31/437 ; A61P37/00 ; A61P35/00 ; A61P9/00
摘要：
The present disclosure provides, inter alia, Compounds of Formula (I) or pharmaceutically acceptable salts thereof that are modulators of the C5a receptor. Also provided are pharmaceutical compositions and methods of use including the treatment of diseases or disorders involving pathologic activation from C5a and non-pharmaceutical applications.