- 专利标题： HEPATITIS B VIRUS (HBV) dsRNA AGENT COMPOSITIONS AND METHODS OF USE THEREOF
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申请号： US17936258申请日： 2022-09-28
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公开(公告)号： US20230128522A1公开(公告)日： 2023-04-27
- 发明人: Vasant R. JADHAV , Martin A. MAIER , Stuart MILSTEIN , Mark K. SCHLEGEL
- 申请人： ALNYLAM PHARMACEUTICALS, INC.
- 申请人地址： US MA Cambridge
- 专利权人： ALNYLAM PHARMACEUTICALS, INC.
- 当前专利权人： ALNYLAM PHARMACEUTICALS, INC.
- 当前专利权人地址： US MA Cambridge
- 主分类号： C12N15/113
- IPC分类号： C12N15/113 ; A61K47/54 ; A61P31/20
摘要：
The present disclosure relates to double stranded RNA agents targeting the hepatitis B virus (HBV) genome, and methods of using such agents to inhibit expression of one or more HBV genes and methods of treating subjects having an HBV infection or HBV-associated disorder, e.g., chronic hepatitis B infection.
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