A production method and device for multimedia work, and a computer-readable storage medium. The method includes: acquiring a target audio and at least one piece of multimedia information, calculating a matching degree between the target audio and the multimedia information, sorting the at least one piece of multimedia information according to the matching degree in a descending order, assigning top-ranking multimedia information as target multimedia information; calculating the image quality of each image in the target multimedia information, sorting every image of the target multimedia information according to image quality in a descending order, assigning the top-ranking images as target images; and synthesizing a multimedia work according to the target images and the target audio. The method allows the acquisition of high-definition multimedia work in which the video content and background music match with each other, and reduces the time cost and learning cost consumed by users in editing videos.