Invention Application
- Patent Title: Synthesis of vinylic alcohol intermediates
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Application No.: US17916843Application Date: 2021-04-28
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Publication No.: US20230136910A1Publication Date: 2023-05-04
- Inventor: Robert P. FARRELL , Jason S. TEDROW
- Applicant: AMGEN INC.
- Applicant Address: US CA Thousand Oaks
- Assignee: AMGEN INC.
- Current Assignee: AMGEN INC.
- Current Assignee Address: US CA Thousand Oaks
- International Application: PCT/US21/29526 WO 20210428
- Main IPC: C07D519/00
- IPC: C07D519/00 ; C07D513/04
Abstract:
Provided herein are processes for synthesizing intermediates useful in preparing Mcl-1 inhibitors. In particular, provided herein are processes for synthesizing compound (E), wherein R1 is described herein. Compound (E) can be useful in synthesizing compound (A1), or a salt or solvate thereof, and compound (A2), or a salt of solvate thereof.
Information query
