- 专利标题： 3-HETEROARYL PYRROLIDINE AND PIPERIDINE OREXIN RECEPTOR AGONISTS
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申请号： US18254190申请日： 2021-12-01
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公开(公告)号： US20240002359A1公开(公告)日： 2024-01-04
- 发明人: Stephane L. Bogen , Ping Chen , Dane James Claussen , Xianhai Huang , Michael T. Rudd , Shawn P. Walsh , Lan Wei , Dexi Yang
- 申请人： Stephane L. BOGEN , Ping CHEN , Dane James CLAUSSEN , Xianhai HUANG , Michael T. RUDD , Shawn P. WALSH , Lan WEI , Dexi YANG , Merck Sharp & Dohme LLC
- 申请人地址： US NJ Kenilworth
- 专利权人： Merck Sharp & Dohme LLC
- 当前专利权人： Merck Sharp & Dohme LLC
- 当前专利权人地址： US NJ Rahway
- 国际申请： PCT/US2021/061344 2021.12.01
- 进入国家日期： 2023-05-24
- 主分类号： C07D401/04
- IPC分类号： C07D401/04 ; C07D417/04 ; C07D401/14 ; C07D403/04 ; C07D405/14 ; C07D413/14
摘要：
The present invention is directed to 3-heteroaryl pyrrolidine and piperidine compounds which are agonists of orexin receptors. The present invention is also directed to uses of the compounds described herein in the potential treatment or prevention of neurological and psychiatric disorders and diseases in which orexin receptors are involved. The present invention is also directed to compositions comprising these compounds. The present invention is also directed to uses of these compositions in the potential prevention or treatment of such diseases in which orexin receptors are involved.
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