A process monitoring device includes: a measuring tube module having at least one measuring tube through which a medium can flow; a receptacle module having a receptacle, wherein the measuring tube module can be inserted into the receptacle, wherein the measuring tube module can be mechanically separably connected to the receptacle module; and a system for biotechnological applications, wherein the system has a housing, wherein the housing has a housing wall, which delimits a housing interior, wherein the housing wall has a cover, wherein the cover has an opening, wherein the receptacle module, in particular the receptacle, extends through the opening into the housing interior.