This application relates to wireless communications, including methods and apparatus to manage uplink (UL) transmit switching with multiple timing advance groups (TAGs) for wireless devices. A wireless device is configured to use multiple carriers selected from a set of available carriers that can be associated with different TAGs. When a second set of carriers, used after switching from a first set of carriers, includes carriers that belong to different TAGs, the wireless device determines whether to transmit on one or more first uplink transmission occasions for each of the carriers in the second set of carriers based on whether a first UL transmission occasion for at least one carrier overlaps a switching gap time period. The wireless device can disallow transmission on first UL transmission occasions of one or more carriers to accommodate the overlap.