- 专利标题: COMPOSITIONS COMPRISING AN ANTI-LAG-3 ANTIBODY OR AN ANTI-LAG-3 ANTIBODY AND AN ANTI-PD-1 OR ANTI-PD-L1 ANTIBODY
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申请号: US18336889申请日: 2023-06-16
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公开(公告)号: US20240066123A1公开(公告)日: 2024-02-29
- 发明人: Lori S. BURTON , William Ying , Nils Lonberg , Sudhir Chakravarthi , Pedro Smith
- 申请人: Bristol-Myers Squibb Company
- 申请人地址: US NJ Princeton
- 专利权人: Bristol-Myers Squibb Company
- 当前专利权人: Bristol-Myers Squibb Company
- 当前专利权人地址: US NJ Princeton
- 分案原申请号: US16616583 2019.11.25
- 主分类号: A61K39/395
- IPC分类号: A61K39/395 ; A61K9/00 ; A61K45/06 ; A61K47/02 ; A61K47/12 ; A61K47/18 ; A61K47/22 ; A61K47/26 ; A61K47/34 ; C07K16/28
摘要:
This provides pharmaceutical compositions that comprise (i) an anti-LAG-3 antibody or antigen binding fragment thereof or (ii) an anti-LAG-3 antibody or antigen binding fragment thereof and an anti-PD-1 antibody, anti-PD-L1 antibody, or antigen binding fragment thereof. Also provided are pharmaceutical compositions that comprise a buffering agent, stabilizing or bulking agent, and a surfactant. The disclosure also provides a vial, syringe, intravenous bag, or kit that comprises the compositions, and methods for using the compositions.
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