Invention Publication
- Patent Title: Methods and Compositions for Treating Leucine Rich Repeat Kinase 2 (LRRK2)-Associated Disorder or Condition
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Application No.: US18226071Application Date: 2023-07-25
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Publication No.: US20240075050A1Publication Date: 2024-03-07
- Inventor: Yulan Xiong , Jianzhong Yu , Qinfang Liu
- Applicant: University of Connecticut
- Applicant Address: US CT Farmington
- Assignee: University of Connecticut
- Current Assignee: University of Connecticut
- Current Assignee Address: US CT Farmington
- Main IPC: A61K31/7056
- IPC: A61K31/7056 ; A61K45/06 ; A61P25/28 ; A61P29/00
Abstract:
The present invention relates to methods and compositions for treating an LRRK2-associate disorder or condition, e.g., Parkinson's Disease, methods for reducing or preventing neuronal cell death, and methods for reducing neurodegeneration and/or neuroinflammation, in a subject in need thereof, by an agent that decreases the expression of LRRK2, e.g., an agent that induces LRRK2 mRNA decay.
Information query
