- 专利标题： METHODS OF USE FOR CAR T CELLS
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申请号： US18459302申请日： 2023-08-31
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公开(公告)号： US20240075069A1公开(公告)日： 2024-03-07
- 发明人: Philip Stewart LOW , Haiyan CHU , Yingjuan June LU , Christopher Paul LEAMON , Leroy W. WHEELER, II , Michael C. JENSEN , James MATTHAEI
- 申请人： ENDOCYTE, INC. , PURDUE RESEARCH FOUNDATION , SEATTLE CHILDREN'S HOSPITAL (DBA SEATTLE CHILDREN'S RESEARCH INSTITUTE)
- 申请人地址： US IN West Lafayette
- 专利权人： ENDOCYTE, INC.,PURDUE RESEARCH FOUNDATION,SEATTLE CHILDREN'S HOSPITAL (DBA SEATTLE CHILDREN'S RESEARCH INSTITUTE)
- 当前专利权人： ENDOCYTE, INC.,PURDUE RESEARCH FOUNDATION,SEATTLE CHILDREN'S HOSPITAL (DBA SEATTLE CHILDREN'S RESEARCH INSTITUTE)
- 当前专利权人地址： US IN West Lafayette
- 分案原申请号： US16253562 2019.01.22
- 主分类号： A61K35/17
- IPC分类号： A61K35/17 ; A61K9/00 ; A61K31/365 ; A61K31/519 ; A61K38/17 ; A61P35/00 ; C07K14/725 ; C07K16/44 ; C07K16/46 ; C12N5/0783
摘要：
The present disclosure relates to methods of treating a patient with a cancer by administering to the patient a composition comprising CAR T cells wherein the CAR T cells comprise a CAR and the CAR comprises an E2 anti-fluorescein antibody fragment, and administering to the patient a small molecule linked to a targeting moiety by a linker. The disclosure also relates to compositions for use in such methods.
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