An efficient heat pump ejector vacuum dryer system and associated method of use for drying items that includes a drying vessel having a condenser and having a first evaporator where the first evaporator has an input that is connected to an output of the first expansion valve, a first expansion valve connected in fluid communication between the condenser and the first evaporator, a second expansion valve connected between the condenser and the second evaporator, a compressor having an input connected to an output of the first evaporator, an ejector that receives a vapor stream from an output of the compressor and receives a vapor stream from the output of the second evaporator generates as an output a high-temperature vapor provided to a condenser of the drying vessel to dry the items and generate an output of moisture, and a water reservoir that accumulates water from the drying vessel.