Invention Publication
- Patent Title: MICROTUBULE DESTABILIZER ADDITIVES TO INCREASE RECOMBINANT VIRAL VECTOR TITERS
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Application No.: US18273053Application Date: 2022-01-21
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Publication No.: US20240101971A1Publication Date: 2024-03-28
- Inventor: Terrence Michael Dobrowsky , Jenny Wang-Yuanzhen Shupe
- Applicant: Biogen MA Inc.
- Applicant Address: US MA Cambridge
- Assignee: Biogen MA Inc.
- Current Assignee: Biogen MA Inc.
- Current Assignee Address: US MA Cambridge
- International Application: PCT/US2022/013310 2022.01.21
- Date entered country: 2023-07-19
- Main IPC: C12N7/00
- IPC: C12N7/00 ; C12M1/00 ; C12N15/85

Abstract:
The present disclosure pertains to methods and compositions for the production of recombinant viral vectors, e.g., recombinant adeno-associated viruses (rAAVs), using at least one microtubule destabilizing agent described herein.
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