- 专利标题: T CELL RECEPTORS THAT BIND TO NY-ESO-1 AND METHODS OF USE THEREOF
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申请号: US18190954申请日: 2023-03-27
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公开(公告)号: US20240102044A1公开(公告)日: 2024-03-28
- 发明人: Marc van Dijk , Volker Seibert , Cornelia Anne Mundt , Arthur Andrew Hurwitz , Mark Adrian Exley , Benjamin Jacob Wolf , Daniel Leventhal , Sébastien Lalevée , Reed Masakayan
- 申请人: MiNK Therapeutics, Inc.
- 申请人地址: US NY New York
- 专利权人: MiNK Therapeutics, Inc.
- 当前专利权人: MiNK Therapeutics, Inc.
- 当前专利权人地址: US NY New York
- 主分类号: C12N15/85
- IPC分类号: C12N15/85 ; A61K47/64 ; A61K47/65 ; C07K14/085 ; C07K14/725 ; C07K14/74 ; C07K16/18
摘要:
Provided are TCRs (e.g., TCRs that bind to NY-ESO-1), cells and pharmaceutical compositions comprising these TCRs, nucleic acids encoding these TCRs, expression vectors and host cells for making these TCRs, and methods of treating a subject using these TCRs.
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