Invention Publication
- Patent Title: Regulation of Butyrophilin subfamily 3 member A1 (BTN3A1, CD277)
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Application No.: US18274307Application Date: 2022-02-04
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Publication No.: US20240115705A1Publication Date: 2024-04-11
- Inventor: Alexander Marson , Murad Mamedov
- Applicant: The J. Gladstone Institutes, a testamentary trust established under the will of J. David Gladstone , The Regents of the University of California
- Applicant Address: US CA San Francisco
- Assignee: The J. Gladstone Institutes, a testamentary trust established under the will of J. David Gladstone,The Regents of the University of California
- Current Assignee: The J. Gladstone Institutes, a testamentary trust established under the will of J. David Gladstone,The Regents of the University of California
- Current Assignee Address: US CA San Francisco
- International Application: PCT/US2022/070520 2022.02.04
- Date entered country: 2023-07-26
- Main IPC: A61K39/00
- IPC: A61K39/00 ; A61K45/06 ; A61P35/00 ; C12N15/86 ; G01N33/50

Abstract:
Described herein are positive and negative regulators of BTN3A, as well as methods for identifying subjects who can benefit from T cell therapies and/or various chemotherapies. The subjects can for example be suffering from immune disorders, cancer and other diseases and conditions.
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