- 专利标题: LIPOCATIONIC DENDRIMERS AND USES THEREOF
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申请号: US18508192申请日: 2023-11-13
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公开(公告)号: US20240116859A1公开(公告)日: 2024-04-11
- 发明人: Daniel J. SIEGWART , Kejin ZHOU
- 申请人: The Board of Regents of The University of Texas System
- 申请人地址: US TX Austin
- 专利权人: The Board of Regents of The University of Texas System
- 当前专利权人: The Board of Regents of The University of Texas System
- 当前专利权人地址: US TX Austin
- 主分类号: C07C321/14
- IPC分类号: C07C321/14 ; A61K9/51 ; A61K31/7105 ; A61K31/7125 ; A61K47/20 ; A61K47/22 ; A61K47/59 ; A61K47/60 ; A61K47/69 ; A61K48/00 ; C07C323/52 ; C07D295/15
摘要:
Modular dendrimers with cationic groups and lipophilic groups are provided herein. In some aspects, the dendrimers provided herein may be formulated in compositions which contain a nucleic acid and one or more helper excipients. In some aspects, these compositions may also be used to treat diseases or disorders with a therapeutic nucleic acid.
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