Invention Publication
- Patent Title: NOVEL JAK-SPECIFIC INHIBITOR COMPOUND AND METHOD FOR PREPARING SAME
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Application No.: US18254927Application Date: 2021-11-29
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Publication No.: US20240116920A1Publication Date: 2024-04-11
- Inventor: Soo Sung KANG , Eun Sun PARK , Eun Hee PARK , Sun Joo LEE , Seung Hee HAN
- Applicant: KOREA PHARMA CO., LTD. , EWHA UNIVERSITY-INDUSTRY COLLABORATION FOUNDATION
- Applicant Address: KR Hwaseong-si, Gyeonggi-do
- Assignee: KOREA PHARMA CO., LTD.,EWHA UNIVERSITY-INDUSTRY COLLABORATION FOUNDATION
- Current Assignee: KOREA PHARMA CO., LTD.,EWHA UNIVERSITY-INDUSTRY COLLABORATION FOUNDATION
- Current Assignee Address: KR Hwaseong-si, Gyeonggi-do
- Priority: KR 20200165017 2020.11.30
- International Application: PCT/KR2021/017797 2021.11.29
- Date entered country: 2023-05-30
- Main IPC: C07D471/04
- IPC: C07D471/04 ; A61P1/16

Abstract:
Provided is a novel JAK-specific inhibitor compound and a method for preparing the same. The compound of the provided can exhibit therapeutic effects on a variety of diseases, for example, inflammatory diseases, autoimmune diseases, myeloproliferative diseases, and human cancers due to its ability to regulate signal transduction at the level of JAK kinases. In particular, due to its high selectivity for JAK1, the compound of the provided can exhibit better therapeutic effects on inflammatory diseases and autoimmune diseases at a low dose and with fewer side effects and can be expected to be effective in preventing and treating liver fibrosis.
Public/Granted literature
- US1937123A Sleeve valve engine Public/Granted day:1933-11-28
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