Invention Publication
- Patent Title: SUBSTITUTED HETEROCYCLIC COMPOUNDS
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Application No.: US18539519Application Date: 2023-12-14
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Publication No.: US20240124421A1Publication Date: 2024-04-18
- Inventor: Steven H. Spergel , Ryan M. Moslin , Michael Edward Mertzman
- Applicant: BRISTOL-MYERS SQUIBB COMPANY
- Applicant Address: US NJ Princeton
- Assignee: BRISTOL-MYERS SQUIBB COMPANY
- Current Assignee: BRISTOL-MYERS SQUIBB COMPANY
- Current Assignee Address: US NJ Princeton
- The original application number of the division: US17743615 2022.05.13
- Main IPC: C07D401/14
- IPC: C07D401/14 ; C07D401/12
Abstract:
There are disclosed compounds of the following formula I:
or a stereoisomer or pharmaceutically acceptable salt thereof, wherein all substituents are as defined herein, which are useful in the modulation of IL-12, IL-23 and/or IFNα, by acting on Tyk-2 to cause signal transduction inhibition. The compounds of the invention may be useful for treating neurodegenerative diseases or disorders.
or a stereoisomer or pharmaceutically acceptable salt thereof, wherein all substituents are as defined herein, which are useful in the modulation of IL-12, IL-23 and/or IFNα, by acting on Tyk-2 to cause signal transduction inhibition. The compounds of the invention may be useful for treating neurodegenerative diseases or disorders.
Information query
