Provided are an air purification device (100) and an air conditioner (1000). The air purification device (100) includes a housing (1), a filter module (2), and a plurality of power supply elements (3). The housing (1) has an accommodation cavity (11). The filter module (2) is disposed within the accommodation cavity (11) and has a plurality of electrical connectors (21) provided thereon and arranged at intervals in a first direction. The plurality of power supply elements (3) are arranged at intervals at the housing (1) in the first direction and have a one-to-one correspondence with the plurality of electrical connectors (21). Each of the plurality of power supply elements (3) has a plurality of power supply contacts (31). When the plurality of electrical connectors (21) is in contact with one of the plurality of power supply contacts (31) of each of the plurality of power supply elements (3), the power supply elements (3) is electrically connected to the electrical connectors (21). Therefore, it is possible to allow for diversified mounting positions of the filter module (2) and improve mounting flexibility of the filter module (2). In addition, optimization of an internal structure of each of the air purification device (100) and the air conditioner (1000) having the air purification device (100) are facilitated.