Invention Publication
- Patent Title: COMBINATION OF NOVEL VACCINES AGAINST ZIKA VIRUS AND DNA ANTIBODY CONSTRUCTS FOR USE AGAINST ZIKA VIRUS
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Application No.: US18477785Application Date: 2023-09-28
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Publication No.: US20240131154A1Publication Date: 2024-04-25
- Inventor: David Weiner , Karuppiah Muthumani , Jian Yan
- Applicant: The Trustees of the University of Pennsylvania , Inovio Pharmaceuticals, Inc. , The Wistar Institute of Anatomy and Biology
- Applicant Address: US PA Philadelphia
- Assignee: The Trustees of the University of Pennsylvania,Inovio Pharmaceuticals, Inc.,The Wistar Institute of Anatomy and Biology
- Current Assignee: The Trustees of the University of Pennsylvania,Inovio Pharmaceuticals, Inc.,The Wistar Institute of Anatomy and Biology
- Current Assignee Address: US PA Philadelphia
- Main IPC: A61K39/42
- IPC: A61K39/42 ; A61K39/12 ; A61P31/14 ; C07K14/18 ; C07K16/10
Abstract:
Disclosed herein is a composition comprising a recombinant nucleic acid sequence that encodes an antibody to a Zika viral antigen, and functional fragments thereof. The invention also relates to a composition comprising the combination of a first composition that elicits an immune response in a mammal against zika virus and a second composition comprising a recombinant nucleic acid sequence encoding an antibody, a fragment thereof, a variant thereof, or a combination thereof. In some instances, the nucleic acid molecule comprises a nucleotide sequence encoding an anti-ZIKV-Envelope (anti-ZIKV E) Protein antibody.
Public/Granted literature
- US20240226291A9 COMBINATION OF NOVEL VACCINES AGAINST ZIKA VIRUS AND DNA ANTIBODY CONSTRUCTS FOR USE AGAINST ZIKA VIRUS Public/Granted day:2024-07-11
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