Methods, apparatus, systems and articles of manufacture are disclosed for audio equalization based on variant selection. An example apparatus to equalize audio includes at least one memory, machine readable instructions, and processor circuity to at least one of instantiate or execute the machine readable instructions to train a neural network model to apply a first audio equalization profile to first audio associated with a first variant of media, and apply a second audio equalization profile to second audio associated with a second variant of media. The processor circuitry is to at least one of instantiate or execute the machine readable instructions to at least one of dispatch or execute the neural network model.