- 专利标题： COMPOSITION FOR IN VIVO DELIVERY OF RNA AND PREPERATION METHOD THEREFOR
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申请号： US18279689申请日： 2022-03-07
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公开(公告)号： US20240148897A1公开(公告)日： 2024-05-09
- 发明人: Yang Je CHO , Seok Hyun KIM , Kwangsung KIM , Shin Ae PARK
- 申请人： EYEGENE INC.
- 申请人地址： KR Seoul
- 专利权人： EYEGENE INC.
- 当前专利权人： EYEGENE INC.
- 当前专利权人地址： KR Seoul
- 优先权： KR 20210029929 2021.03.08
- 国际申请： PCT/KR2022/003220 2022.03.07
- 进入国家日期： 2023-08-31
- 主分类号： A61K47/69
- IPC分类号： A61K47/69 ; A61K8/14 ; A61K9/127 ; A61K39/215 ; A61K39/39 ; A61K47/54
摘要：
The present disclosure relates to a mRNA delivery composition comprising cationic lipid-based liposome. The mRNA delivery composition according to the present disclosure is superb in terms of storage stability and exhibits high intracellular delivery and expression rates in vivo and thus, can enhance the stability and efficiency of mRNA vaccines for cancer therapy or mRNA vaccines for prevention of viral infections.
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