A computer-implemented system is provided that includes a plurality of endpoint databases employed to store medical images and metadata that describes attributes of the respective medical images. A management and orchestration platform periodically scans the endpoint databases to determine an index of the recently acquired medical images and associated metadata and updates to metadata associated with previously stored medical images. A search engine executes the search function to retrieve at least one of the recently acquired medical images and associated metadata and the recent updates to metadata associated with the previously stored medical images. The platform can also provide project management services and various collaborative, social networking type services. For example, the platform can facilitate collaborative review of medical image data, allowing users to rate and review the medical image data, annotate the medical image data, edit and augment the medical image data, and the like.