An electrical stimulation device includes a control circuit, a power supply circuit, and an electrical stimulation circuit. The power supply circuit provides a first power supply signal. The electrical stimulation circuit is controlled by the control circuit to generate an electrical stimulation signal according to the first power supply signal. The electrical stimulation signal includes two burst signals. A burst duty cycle of the first burst signal ranges from 0.0005% to 50%. A burst frequency of the first burst signal ranges from 0.1 Hz to 200 Hz. The burst signals are monophasic burst signals with opposite polarities or both are biphasic burst signals. Pulse frequencies of pulses in the monophasic burst signals and the biphasic burst signals range from 1000 Hz to 10 million Hz. Pulse duty cycles of the pulses in the monophasic burst signals and the biphasic burst signals range from 0.01% to 50%.