- 专利标题： REPROGRAMMING OF NON-NEURONAL CELLS INTO NEURONS AND METHODS AND COMPOSITIONS TO TREAT NEURODEGENERATIVE DISEASES AND DISORDERS
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申请号： US18323956申请日： 2023-05-25
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公开(公告)号： US20240218362A1公开(公告)日： 2024-07-04
- 发明人: Xiang-Dong Fu , Hao Qian
- 申请人： The Regents of the University of California
- 申请人地址： US CA Oakland
- 专利权人： The Regents of the University of California
- 当前专利权人： The Regents of the University of California
- 当前专利权人地址： US CA Oakland
- 主分类号： C12N15/113
- IPC分类号： C12N15/113 ; A61P25/16 ; C12N5/0793
摘要：
Provided herein is a method of reprogramming a non-neuronal cell to a neuron. Aspects of the present disclosure relate to using cell reprogramming agent suppresses the expression or activity of PTB to convert a non-neuronal cell into a neuron. Also provided herein is a method of treating neurodegenerative disease by reprogramming non-neuronal cells in vivo to functional neurons.
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