The present disclosure provides a display apparatus, a display panel, and a method of driving a display panel. The display panel includes: a base substrate; a pixel array disposed on the base substrate, and including one or more pixel groups each of which includes a plurality of pixels; and a plurality of pixel driving chips disposed on the base substrate and configured to drive the pixel array to display, each of the pixel driving chips including a data signal terminal for receiving data signals and a control signal terminal, where for each of the pixel groups, the plurality of pixels in the pixel group are connected to a common pixel driving chip. A display frame of the display panel includes an address assignment stage and a data signal transmission stage. The method includes: inputting the control signal to the control signal terminal and inputting a first data signal to the data signal terminal in the address assignment stage; and inputting a second data signal to the data signal terminal in the data signal transmission stage. The present disclosure can reduce the number of signal lines and reduce power consumption.