An artificial or simulated skull for use as a medical training device includes a skull cap that can be secured to a skull base at an opening defined by the skull base. One or more vessels for holding fluid, such as simulated blood, may be secured or incorporated into the simulated skull. A trainee, such as a medical student, may perform a practice procedure on the simulated skull, such as a drilling procedure in which the trainee uses a surgical tool to create one or more burr holes in the skull cap before penetrating the vessel containing the simulated blood. Once the skull cap has been excessively damaged from use in one or more practice procedures, it may be replaced with a new skull cap that can be secured to the original skull base.