Examples relate to a system for a scientific or surgical imaging system, to a scientific or surgical imaging system comprising such a system, and to a corresponding method and computer program. The system comprises one or more processors and one or more storage devices. The system is configured to obtain information on one or more illumination parameters used by an illumination system, the illumination system being separate from the scientific or surgical optical imaging system, from the illumination system. The system is configured to determine at least one parameter for using an optical imaging sensor of an imaging device of the scientific or surgical optical imaging system based on the one or more illumination parameters.