A method include of delivering a heart valve prosthesis includes loading the heart valve prosthesis in a crimped configuration within a dilator shaft, tracking the dilator shaft within a vasculature of a patient to a desired site with the heart valve prosthesis loaded therewithin, advancing a delivery device through the dilator shaft to the distal end of the dilator shaft, advancing the delivery device through the heart valve prosthesis to load the heart valve prosthesis onto the delivery device, advancing the delivery device with the heart valve prosthesis mounted thereon past the distal end of the dilator shaft to a treatment site within the vasculature of the patient, and deploying the heart valve prosthesis from the delivery device at the treatment site.