发明公开
- 专利标题: PEPTIDE DRUG CONJUGATES
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申请号: US18570814申请日: 2022-06-20
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公开(公告)号: US20240316059A1公开(公告)日: 2024-09-26
- 发明人: Antonio BERMEJO GOMEZ , Praveen KUMAR CHINTHAKINDI , Charles DEMMER , Katarina FARNEGARDH , Mathias FARNEGARDH , Fredrik LEHMANN , Ellen SANTANGELO
- 申请人: Oncopeptides AB
- 申请人地址: SE Stockholm
- 专利权人: Oncopeptides AB
- 当前专利权人: Oncopeptides AB
- 当前专利权人地址: SE Stockholm
- 优先权: GB 08818.2 2021.06.18
- 国际申请: PCT/EP2022/066756 2022.06.20
- 进入国家日期: 2023-12-15
- 主分类号: A61K31/5377
- IPC分类号: A61K31/5377 ; A61K31/4184 ; A61K31/437 ; A61K45/06 ; A61P35/00 ; C07D235/16 ; C07D471/04
摘要:
The invention provides compounds of formula (I), that are peptidase enhanced cytotoxics. The invention further provides pharmaceutical compositions comprising the compounds, and the use of the compounds or pharmaceutical compositions as a medicament, particularly for use in the treatment or prophylaxis of cancers such as multiple myeloma, osteosarcoma, breast cancer, lung cancer, ovarian cancer, leukaemia and lymphoma.
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IPC分类: