A family of catalysts for oxygen evolution reaction (OER) in alkaline condition is disclosed. The catalysts utilize elements which are abundant on earth, leading to lower costs compared to IrO2 catalysts. The catalysts can be used in the anode of an anion exchange membrane-based water electrolyzer. The family of new catalysts comprises Ni, Fe, M, B, and O, where M is a metal from Group VIB, Group VIII, and elements 57-71 of the Periodic Table. The catalyst has a layered double hydroxide structure. Methods of making the catalysts are also described.