The present technology relates to an autonomous mobile body, an information processing method, and a program enabling improvement in ability of expression by audio of an autonomous mobile body. An autonomous mobile body includes a recognition unit that recognizes an external stimulus, and an audio control unit that controls a characteristic and an output timing of audio output in response to the stimulus on the basis of at least one of a behavior of the autonomous mobile body, a state of the autonomous mobile body, a partner who gives the stimulus, a surrounding situation, or a content of the stimulus. The present technology can be applied to, for example, a pet-type robot.