The present technology relates to an autonomous mobile body, an information processing method, and a program enabling improvement in ability of expression by audio of an autonomous mobile body. An autonomous mobile body includes an operation control unit that controls an operation of the autonomous mobile body, a recognition unit that recognizes a state of the autonomous mobile body in operation, and an audio control unit that generates or processes audio data corresponding to audio to be output in accordance with the operation of the autonomous mobile body on the basis of a recognition result of the state of the autonomous mobile body, and controls a characteristic and an output timing of the audio. The present technology can be applied to, for example, a pet-type robot.