Techniques are provided for non-integer interpolation for signal sampling. A system implementing the techniques according to an embodiment includes a memory configured to store frequency values associated with an input signal sampled at a first clock rate. The system also includes a clock phase detector configured to detect phase alignment between a first clock signal associated with the first clock rate and a second clock signal associated with a second clock rate. The system further includes a read circuit configured to adjust an interpolation time interval in response to the detected phase alignment and to read the frequency values from the memory at the adjusted interpolation time interval. The system further includes a phase accumulator configured to accumulated phase as a sum of the frequency values read from the memory. The system further includes a waveform generator configured to generate an output waveform sample based on the accumulated phase.