Invention Application
- Patent Title: BISPECIFIC ANTIBODY AND APPLICATION THEREOF
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Application No.: US18692312Application Date: 2022-09-29
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Publication No.: US20240383974A1Publication Date: 2024-11-21
- Inventor: Wenxin XU , Xuefei FANG , Deyu XU , Jieying XU , Lieming DING
- Applicant: BETTA PHARMACEUTICALS CO., LTD
- Applicant Address: CN Hangzhou
- Assignee: BETTA PHARMACEUTICALS CO., LTD
- Current Assignee: BETTA PHARMACEUTICALS CO., LTD
- Current Assignee Address: CN Hangzhou
- Priority: CN202111162303.X 20210930
- International Application: PCT/CN2022/122367 WO 20220929
- Main IPC: C07K16/22
- IPC: C07K16/22 ; A61K39/00 ; A61P35/00 ; C07K16/28
Abstract:
Provided are a bispecific antibody and use thereof. The bispecific antibody provided can specifically bind to TGF-β, GARP, or GARP-TGF-β complex individually or simultaneously, and can also specifically bind to PD-L1. The bispecific antibody provided exhibits high affinity and specificity for the antigens, has a tumor-killing effect, and can be applied to the treatment of tumors.
Information query
