Invention Application
- Patent Title: SPIROCYCLIC BICYCLIC MODULATORS OF CHOLESTEROL BIOSYNTHESIS AND THEIR USE FOR PROMOTING REMYELINATION
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Application No.: US18670537Application Date: 2024-05-21
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Publication No.: US20240391930A1Publication Date: 2024-11-28
- Inventor: Marie-Gabrielle BRAUN , Georgette CASTANEDO , William VERNIER , Matthew VOLGRAF , Michael SIU , James Guy BREITENBUCHER
- Applicant: GENENTECH, INC. , CONVELO THERAPEUTICS, INC.
- Applicant Address: US CA SOUTH SAN FRANCISCO; US OH Cleveland
- Assignee: GENENTECH, INC.,CONVELO THERAPEUTICS, INC.
- Current Assignee: GENENTECH, INC.,CONVELO THERAPEUTICS, INC.
- Current Assignee Address: US CA SOUTH SAN FRANCISCO; US OH Cleveland
- Main IPC: C07D495/10
- IPC: C07D495/10 ; A61K31/4155 ; A61K31/4196 ; A61K31/438 ; A61K31/4439 ; A61K31/444 ; A61K31/506
Abstract:
The subject matter described herein is directed to myelin-promoting compounds of Formula I and pharmaceutical salts thereof, methods of preparing the compounds, pharmaceutical compositions comprising the compounds, and methods of administering the compounds for the treatment of disorders, such as myelin-related disorders.
Information query
