A sour production fluid mitigation system may at an entry point below an injection sub for a coiled tubing system, pumping an inhibited fluid through pressure control equipment for the coiled tubing system to an exit point. A sour production fluid mitigation system may use a choke guide below the exit point and above a wellhead, maintaining an inhibited fluid pressure at the exit point greater than or equal to a production fluid pressure at a production tree of the wellhead.