This disclosure is directed radio link control (RLC) and media access control (MAC) protocol data unit (PDU) transmission and retransmission in wireless networks, and is particularly directed to methods and systems for preventing inconsistency in RLC transmission status reports, and for resolving such inconsistency. The disclosed solutions either proactively prevent or reduce the likelihood of the occurrence of such inconsistency at the MAC layer or provide remedial measures at the RLC layer after an inconsistent RLC report is received. The disclosed methods and systems help improving network efficiency.