Invention Application
- Patent Title: COMBINATIONS OF KRAS G12D INHIBITORS WITH PI3Ka INHIBITORS AND RELATED METHODS OF TREATMENT
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Application No.: US18694848Application Date: 2022-10-04
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Publication No.: US20240408098A1Publication Date: 2024-12-12
- Inventor: Jill Hallin , James Gail Christensen , Vickie Bowcut , Peter Olson
- Applicant: MIRATI THERAPEUTICS, INC.
- Applicant Address: US CA San Diego
- Assignee: MIRATI THERAPEUTICS, INC.
- Current Assignee: MIRATI THERAPEUTICS, INC.
- Current Assignee Address: US CA San Diego
- International Application: PCT/US2022/045619 WO 20221004
- Main IPC: A61K31/519
- IPC: A61K31/519 ; A61K31/4439 ; A61P35/00
Abstract:
The present invention relates to combination therapies for treating KRas G12D cancers: in particular, the present invention relates to methods of treating cancer in a subject in need thereof, comprising administering to the subject a therapeutically effective amount of a combination of a PI3Ka inhibitor and a KRas G12D inhibitor, pharmaceutical compositions comprising a such compositions, kits comprising such compositions and methods of use thereof.
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